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Sodium gualenate

CAS No. 6223-35-4

Sodium gualenate ( Guaiazulenesulfonate sodium )

产品货号. M20600 CAS No. 6223-35-4

愈创木酸钠(愈创蓝油磺酸钠)是愈创蓝油烯 (GA) 的亲水衍生物,是一种不稳定的化合物。它具有抗炎和伤口愈合作用。

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
100MG ¥462 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    Sodium gualenate
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    愈创木酸钠(愈创蓝油磺酸钠)是愈创蓝油烯 (GA) 的亲水衍生物,是一种不稳定的化合物。它具有抗炎和伤口愈合作用。
  • 产品描述
    Sodium gualenate (Guaiazulenesulfonate sodium) a hydrophilic derivative of guaiazulene (GA) is an unstable compound.?It has anti-inflammatory and wound-healing effects.??(In Vitro):Sodium gualenate is an unstable compound, which is gradually decomposed in the solid state at room temperature. When heated, Sodium gualenate decomposes almost completely within 1 week. It was found that a kneaded mixture of Sodium gualenate and cornstarch (weight ratio; 1:250) for tableting with water is stable. So, during production, Sodium gualenate could be stabilized using water. Sodium gualenate slightly inhibits the histamine release from rat peritoneal mast cells and strongly inhibits the leukocyte emigration induced by fMLP.(In Vivo):Sodium gualenate has been frequently used for the treatment of human gastritis. Cytoprotection is defined as the main mechanism of Sodium gualenate to protect the mucosa of the stomach and the antipeptic actions in vivo have also been shown.
  • 体外实验
    ——
  • 体内实验
    ——
  • 同义词
    Guaiazulenesulfonate sodium
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    Others
  • 研究领域
    Others
  • 适应症
    folic acid antagonists

化学信息

  • CAS Number
    6223-35-4
  • 分子量
    300.35
  • 分子式
    C15H17NaO3S
  • 纯度
    >98% (HPLC)
  • 溶解度
    DMSO:30 mg/mL (99.88 mM)
  • SMILES
    [Na+].CC(C)c1ccc(C)c2c(cc(C)c2c1)S([O-])(=O)=O
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Cao T Li Y Yang Z et al. Synthesis and Biological Evaluation of 3 8-dimethyl-5-isopropylazulene Derivatives as Anti-gastric Ulcer Agent[J]. Chemical Biology & Drug Design 2016 88(2):264-271.
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